Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 9/20 | 0.46 |
| ▸ | CD69 | Q07108 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.45 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.45 |
| ▸ | RIOK1 | Q9BRS2 | 1/20 | 0.45 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.45 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25167752 | 1.00 | BTK (0.46) | BTKCD69JAK2CYP3A4HRH2 | |
| SCHEMBL30913579 | 0.84 | BTK (0.52) | BTKCD69JAK2CYP3A4HRH2 | |
| SCHEMBL25176696 | 0.84 | BTK (0.52) | BTKCD69JAK2CYP3A4HRH2 | |
| SCHEMBL25584105 | 0.82 | BTK (0.38) | BTKCD69JAK2CYP3A4HRH2 | |
| SCHEMBL25169911 | 0.78 | BTK (0.49) | BTKCD69JAK2CYP3A4HRH2 | |
| SCHEMBL30434223 | 0.78 | BTK (0.49) | BTKCD69JAK2CYP3A4HRH2 | |
| SCHEMBL16794224 | 0.77 | BTK (0.69) | BTKCD69JAK2CYP3A4HRH2 | |
| SCHEMBL29676750 | 0.77 | BTK (0.69) | BTKCD69JAK2CYP3A4HRH2 | |
| SCHEMBL25169920 | 0.72 | BTK (0.51) | BTKCD69JAK2CYP3A4HRH2 | |
| SCHEMBL16794214 | 0.72 | BTK (0.71) | BTKCD69CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159532-A | Compound with BTK protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-06-07 | — | — | CN | disclosed |