SCHEMBL30915330

SCHEMBL30915330

CC(C)(C)OC(=O)N1Cc2nc(Cl)ncc2C1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK17B O94768 1/20 0.36
STK17A Q9UEE5 1/20 0.36
PIK3CA P42336 2/20 0.35
MTOR P42345 2/20 0.35
MAPT P10636 2/20 0.35
POLB P06746 1/20 0.34
ELANE P08246 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRA6 Q16445 1/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
MAPK1 P28482 1/20 0.32
CKS1B P61024 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29964392 0.88 MAPT (0.38) STK17BSTK17APIK3CAMTORMAPT
SCHEMBL30915381 0.76 POLB (0.36) PIK3CAMTORPOLBHDAC1HDAC6
SCHEMBL30825171 0.76 SMN1; SMN2 (0.39) STK17BSTK17APIK3CAMTORMAPT
SCHEMBL15875047 0.74 DDB1 (0.53) STK17BSTK17AMAPTPOLBDDB1
SCHEMBL18789182 0.72 POLB (0.44) PIK3CAMTORPOLBELANEGABRA1
SCHEMBL29222584 0.72 HSP90AA1 (0.37) STK17BSTK17APIK3CAMTORMAPT
SCHEMBL30543372 0.72 HSP90AA1 (0.37) STK17BSTK17APIK3CAMTORMAPT
SCHEMBL30915373 0.72 CKS1B (0.42) PIK3CAMTORPOLBCKS1BSKP1
SCHEMBL17183931 0.71 MAPT (0.65) MAPTPOLBDDB1CRBNHSP90AA1
SCHEMBL31643715 0.71 HSP90AA1 (0.37) PIK3CAMTORPOLBGABRA1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626888-A1 COMPOUNDS Redx Pharma Limited (GB) 2025-10-08 EP disclosed
WO-2024115890-A1 COMPOUNDS REDX PHARMA PLC (GB) 2024-06-06 WO disclosed