Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18477510 | 1.00 | NR1H2 (0.46) | NR1H2NR1H3GPR119DPP7NPC1 | |
| SCHEMBL30915772 | 1.00 | NR1H2 (0.46) | NR1H2NR1H3GPR119DPP7NPC1 | |
| SCHEMBL20054395 | 0.97 | NR1H2 (0.49) | NR1H2NR1H3GPR119NPC1HSD17B10 | |
| SCHEMBL5755507 | 0.97 | NR1H2 (0.49) | NR1H2NR1H3GPR119NPC1HSD17B10 | |
| SCHEMBL19564479 | 0.97 | NR1H2 (0.49) | NR1H2NR1H3GPR119NPC1HSD17B10 | |
| SCHEMBL31726992 | 0.83 | HSD17B10 (0.53) | GPR119NPC1HSD17B10HPGD | |
| SCHEMBL31664994 | 0.83 | DPP4 (0.53) | NR1H2GPR119HSD17B10PREP | |
| SCHEMBL4292802 | 0.83 | DPP4 (0.53) | NR1H2GPR119HSD17B10PREP | |
| SCHEMBL17948013 | 0.83 | DPP4 (0.53) | NR1H2GPR119HSD17B10PREP | |
| SCHEMBL17226184 | 0.83 | DPP4 (0.53) | NR1H2GPR119HSD17B10PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076599-A | Dioxazines and their use in the treatment of GBA related diseases | 泽拉丹麦有限公司 | 2024-05-24 | — | — | CN | disclosed |