Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34461120 | 0.94 | AAK1 (0.40) | AAK1RENMMP13 | |
| SCHEMBL30916086 | 0.88 | AAK1 (0.40) | AAK1RENMMP13 | |
| SCHEMBL27032866 | 0.84 | AAK1 (0.40) | AAK1RENMMP13 | |
| SCHEMBL27130846 | 0.84 | AAK1 (0.40) | AAK1RENMMP13 | |
| SCHEMBL31522778 | 0.84 | AAK1 (0.41) | AAK1RENMMP13 | |
| SCHEMBL30916053 | 0.82 | AAK1 (0.41) | AAK1RENMMP13 | |
| SCHEMBL69223 | 0.81 | AAK1 (0.48) | AAK1RENMMP13 | |
| SCHEMBL67031 | 0.81 | AAK1 (0.48) | AAK1RENMMP13 | |
| SCHEMBL38056 | 0.81 | AAK1 (0.48) | AAK1RENMMP13 | |
| SCHEMBL30639575 | 0.80 | AAK1 (0.44) | AAK1RENMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587443-A1 | MACROCYCLIC CFTR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024056798-A1 | MACROCYCLIC CFTR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-03-21 | — | — | WO | disclosed |