Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 12/20 | 0.83 |
| ▸ | NPC1 | O15118 | 8/20 | 0.83 |
| ▸ | RAB9A | P51151 | 8/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.83 |
| ▸ | MEN1 | O00255 | 6/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16681363 | 0.95 | SCD (0.88) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31243 | 0.91 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16562031 | 0.91 | SCD (0.73) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31065 | 0.90 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4912951 | 0.89 | SCD (1.00) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2753553 | 0.88 | SCD (0.93) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4915964 | 0.88 | SCD (0.84) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4913650 | 0.88 | SCD (0.88) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4920310 | 0.88 | SCD (0.88) | SCDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16554145 | 0.88 | SCD (0.88) | SCDNPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609089-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |