Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 20/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590943 | 0.93 | DRD4 (0.62) | DRD4DRD2DRD3 | |
| SCHEMBL6246215 | 0.93 | DRD4 (0.62) | DRD4DRD2DRD3 | |
| SCHEMBL26136158 | 0.80 | DRD4 (0.56) | DRD4DRD2DRD3 | |
| SCHEMBL30194850 | 0.80 | DRD4 (0.56) | DRD4DRD2DRD3 | |
| SCHEMBL16932256 | 0.80 | DRD4 (0.56) | DRD4DRD2DRD3 | |
| SCHEMBL28683509 | 0.80 | DRD4 (0.72) | DRD4DRD2DRD3 | |
| SCHEMBL4312139 | 0.79 | DRD4 (0.60) | DRD4DRD2DRD3 | |
| SCHEMBL12090230 | 0.79 | BCHE (0.58) | — | |
| SCHEMBL2454072 | 0.79 | BCHE (0.58) | — | |
| SCHEMBL1698268 | 0.78 | DRD4 (0.56) | DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622716-A1 | SPIROCYCLIC DIHYDROPYRANOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112654-A1 | SPIROCYCLIC DIHYDROPYRANOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2024-05-30 | — | — | WO | disclosed |