SCHEMBL30919288

SCHEMBL30919288

CCOC(=O)[C@H](CCC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.54
▸ CASP3 P42574 2/20 0.52
▸ PTPN1 P18031 3/20 0.51
▸ TLR2 O60603 2/20 0.51
▸ MDM4 O15151 2/20 0.49
▸ TP53 P04637 2/20 0.49
▸ MDM2 Q00987 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4300738 0.93 KMT2A (0.58) KMT2ACASP3PTPN1TLR2MDM4
SCHEMBL20504185 0.93 KMT2A (0.58) KMT2ACASP3PTPN1TLR2MDM4
SCHEMBL29650664 0.93 KMT2A (0.58) KMT2ACASP3PTPN1TLR2MDM4
SCHEMBL38664780 0.91 TLR2 (0.54) KMT2ACASP3PTPN1TLR2MDM4
SCHEMBL17826082 0.91 KMT2A (0.56) KMT2ACASP3PTPN1TLR2MDM4
SCHEMBL13658468 0.91 KMT2A (0.56) KMT2ACASP3PTPN1TLR2MDM4
SCHEMBL29400679 0.91 KMT2A (0.56) KMT2ACASP3PTPN1TLR2MDM4
SCHEMBL12928621 0.91 KMT2A (0.56) KMT2ACASP3PTPN1TLR2MDM4
SCHEMBL23421235 0.90 TLR2 (0.49) KMT2ACASP3PTPN1TLR2MDM4
SCHEMBL13996828 0.90 TLR2 (0.49) KMT2ACASP3TLR2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4612124-A1 AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY The Johns Hopkins University (US) 2025-09-10 — — EP disclosed
WO-2024097320-A1 AZOTOMYCIN PRODRUGS WITH PREFERENTIAL TUMOR DELIVERY THE JOHNS HOPKINS UNIVERSITY (US) 2024-05-10 — — WO disclosed
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