Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382311 | 0.79 | TSHR (0.51) | SMN1; SMN2NPC1RAB9AKMT2AHTR2C | |
| SCHEMBL9636938 | 0.79 | TSHR (0.51) | SMN1; SMN2NPC1RAB9AKMT2AHTR2C | |
| SCHEMBL21961574 | 0.79 | TSHR (0.51) | SMN1; SMN2NPC1RAB9AKMT2AHTR2C | |
| SCHEMBL10137745 | 0.79 | TSHR (0.51) | SMN1; SMN2NPC1RAB9AKMT2AHTR2C | |
| SCHEMBL1077276 | 0.79 | TSHR (0.51) | SMN1; SMN2NPC1RAB9AKMT2AHTR2C | |
| SCHEMBL23485377 | 0.79 | TSHR (0.51) | SMN1; SMN2NPC1RAB9AKMT2AHTR2C | |
| Hydrochloric Acid SCHEMBL19946512 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4814264 | 0.79 | MEN1 (0.76) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3970912 | 0.79 | MEN1 (0.76) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL379160 | 0.79 | MEN1 (0.76) | SMN1; SMN2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119609-A | Imidazole derivatives and their use as antibiotics | 豪夫迈·罗氏有限公司 | 2024-05-31 | — | — | CN | disclosed |