Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3092086 | 1.00 | KCNH2 (0.39) | KCNH2KMT2A | |
| SCHEMBL3092083 | 1.00 | KCNH2 (0.39) | KCNH2KMT2A | |
| SCHEMBL3076694 | 1.00 | KCNH2 (0.39) | KCNH2KMT2A | |
| SCHEMBL3078696 | 0.92 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL3066735 | 0.92 | KCNH2 (0.41) | KCNH2KMT2A | |
| SCHEMBL3066738 | 0.92 | KCNH2 (0.41) | KCNH2KMT2A | |
| SCHEMBL3066731 | 0.92 | KCNH2 (0.41) | KCNH2KMT2A | |
| SCHEMBL2453135 | 0.92 | KCNH2 (0.41) | KCNH2KMT2A | |
| SCHEMBL3726670 | 0.90 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL14184725 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445476-B2 | Carbacephem β-lactam antibiotics | ACHAOGEN, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | MGAM, MGAM2, B2M | KCNH2 3205/4885KMT2A 819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.