SCHEMBL30921690

SCHEMBL30921690

CC(C)OC(=O)OCOP(=O)(OC[C@@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@@H](C(C)(C)C(=O)O)[C@@H]1C(C)(C)C(=O)O)Oc1ccc(C(C)(C)C)cc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.34
▸ FAP Q12884 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30921685 0.93 TMPRSS2 (0.35) TMPRSS2
SCHEMBL30921679 0.93 TMPRSS2 (0.35) TMPRSS2
SCHEMBL30921688 0.93 TMPRSS2 (0.35) TMPRSS2
SCHEMBL30921672 0.93 TMPRSS2 (0.34) TMPRSS2FAP
SCHEMBL30921669 0.92 TMPRSS2 (0.35) TMPRSS2
SCHEMBL30921701 0.92 TMPRSS2 (0.35) TMPRSS2
SCHEMBL31684073 0.90 TMPRSS2 (0.42) TMPRSS2FAP
SCHEMBL30939817 0.90 TMPRSS2 (0.42) TMPRSS2FAP
SCHEMBL31684069 0.90 TMPRSS2 (0.42) TMPRSS2FAP
SCHEMBL30921695 0.88 TMPRSS2 (0.33) TMPRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118165034-A Nucleotide compound, composition and application thereof 深圳市塔吉瑞生物医药有限公司 2024-06-11 — — CN disclosed
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