Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.66 |
| ▸ | BACE1 | P56817 | 1/20 | 0.66 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.66 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.62 |
| ▸ | MC4R | P32245 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924045 | 0.93 | ACKR3 (0.62) | SIGMAR1ACKR3EPHX2 | |
| SCHEMBL30924124 | 0.90 | EPHX2 (0.63) | SIGMAR1P2RX7ACKR3EPHX2MC4R | |
| SCHEMBL30924056 | 0.90 | ACKR3 (0.61) | SIGMAR1ACHEACKR3EPHX2 | |
| SCHEMBL30924049 | 0.89 | EPHX2 (0.64) | ACKR3EPHX2 | |
| SCHEMBL30924122 | 0.89 | ACKR3 (0.58) | SIGMAR1ACKR3EPHX2 | |
| SCHEMBL30924086 | 0.89 | ACKR3 (0.58) | ACKR3EPHX2 | |
| SCHEMBL30924075 | 0.89 | KCNH2 (0.57) | SIGMAR1ACKR3EPHX2 | |
| SCHEMBL30924018 | 0.89 | ERCC1 (0.65) | ACKR3EPHX2 | |
| SCHEMBL30924121 | 0.89 | ACKR3 (0.58) | SIGMAR1ACKR3EPHX2 | |
| SCHEMBL30924102 | 0.89 | ACKR3 (0.58) | SIGMAR1BCHEACHEBACE1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618985-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | Universitat De Barcelona (ES) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105234-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | UNIVERSITAT DE BARCELONA (ES) | 2024-05-23 | — | — | WO | disclosed |