Sugi Predict

Sugi Predict / Compounds / SCHEMBL30924728

SCHEMBL30924728

SCHEMBL30924728

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CS)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ EPHA2 P29317 2/20 0.65
▸ KDM1A O60341 3/20 0.61
▸ TFPI P10646 6/20 0.59
▸ MAPK8 P45983 1/20 0.59
▸ MAPK9 P45984 1/20 0.59
▸ MAPK10 P53779 1/20 0.59
▸ MAOB P27338 1/20 0.59
▸ KDM5A P29375 1/20 0.59
▸ KDM1B Q8NB78 1/20 0.59
▸ NPY2R P49146 5/20 0.58
▸ NPY4R P50391 5/20 0.58
▸ NPY5R Q15761 5/20 0.58
▸ NPY1R P25929 4/20 0.58
▸ NMUR2 Q9GZQ4 2/20 0.58
▸ NMUR1 Q9HB89 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30924747 0.96 MAPK8 (0.61) EPHA2KDM1ATFPIMAPK8MAPK9
SCHEMBL29903316 0.91 NPY2R (0.64) EPHA2KDM1ATFPIMAOBKDM5A
SCHEMBL29903384 0.90 NPY2R (0.66) EPHA2KDM1ATFPIMAPK8MAPK9
SCHEMBL29695639 0.90 TFPI (0.62) EPHA2KDM1ATFPIMAPK8MAPK9
SCHEMBL29828704 0.89 NMUR2 (0.62) EPHA2KDM1AMAPK8MAPK9MAPK10
SCHEMBL30906429 0.89 EPHA2 (0.60) EPHA2MAPK8MAPK9MAPK10NPY2R
SCHEMBL30605455 0.89 MAPK8 (0.61) EPHA2KDM1AMAPK8MAPK9MAPK10
SCHEMBL29856103 0.88 TFPI (0.60) EPHA2KDM1ATFPIMAOBKDM5A
SCHEMBL30335630 0.88 NMUR2 (0.64) EPHA2TFPINPY2RNPY4RNPY5R
SCHEMBL31182747 0.87 CALCR (0.61) KDM1ATFPINPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026787-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION GLO PHARMA, INC. 2025-01-23 — — US disclosed
US-12162956-B2 Peptides and methods for reducing skin pigmentation GLO PHARMA, INC. (US) 2024-12-10 — — US disclosed
US-20240190917-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION GLO PHARMA, INC. 2024-06-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190917-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION MC1R, TYR, MC5R EPHA2 1524/4885KDM1A 3888/4885TFPI 918/4885
US-12162956-B2 Peptides and methods for reducing skin pigmentation MC1R, TYR, MC5R EPHA2 1524/4885KDM1A 3888/4885TFPI 918/4885
US-20250026787-A1 PEPTIDES AND METHODS FOR REDUCING SKIN PIGMENTATION MC1R, TYR, MC5R EPHA2 1524/4885KDM1A 3888/4885TFPI 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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