SCHEMBL30925714

COc1cc(/C=C/C(=O)O[C@@H]2[C@H](O)C[C@]3(C)[C@H]4CC=C5[C@H]6[C@](C(=O)O)(CC[C@@H](C)[C@@]6(C)O)CC[C@@]5(C)[C@]4(C)CC[C@H]3C2(C)C)ccc1O

nearest known ligand 0.85

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	GYS2	P54840	1/20	0.85

▸	SENP1	Q9P0U3	2/20	0.61

▸	PDE4D	Q08499	2/20	0.61

▸	PDE5A	O76074	1/20	0.61

▸	PDE9A	O76083	1/20	0.61

▸	PDE1B	Q01064	1/20	0.61

▸	HSD11B1	P28845	1/20	0.57

▸	ACHE	P22303	1/20	0.56

▸	PTPN1	P18031	3/20	0.54

▸	PLCG1	P19174	6/20	0.54

▸	POLB	P06746	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29649785	0.90	PDE4D (0.73)	GYS2SENP1PDE4DPDE5APDE9A
SCHEMBL29649857	0.90	PDE4D (0.73)	GYS2SENP1PDE4DPDE5APDE9A
SCHEMBL12181490	0.90	PDE4D (0.73)	GYS2SENP1PDE4DPDE5APDE9A
SCHEMBL24433073	0.90	PDE4D (0.73)	GYS2SENP1PDE4DPDE5APDE9A
SCHEMBL12181496	0.90	PDE4D (0.73)	GYS2SENP1PDE4DPDE5APDE9A
SCHEMBL24433072	0.90	PDE4D (0.73)	GYS2SENP1PDE4DPDE5APDE9A
SCHEMBL15163884	0.85	PDE4D (0.68)	GYS2SENP1PDE4DPDE5APDE9A
SCHEMBL15163880	0.85	PDE4D (0.68)	GYS2SENP1PDE4DPDE5APDE9A
SCHEMBL13637888	0.84	POLB (0.68)	GYS2PDE4DPDE5APDE9APDE1B
SCHEMBL13487367	0.84	POLB (0.68)	GYS2PDE4DPDE5APDE9APDE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4630026-A1	COMPOSITIONS COMPRISING SANGUISORBA OFFICINALIS ROOT EXTRACT AND USES THEREOF	CLARIANT INTERNATIONAL LTD (CH)	2025-10-15	—	—	EP	disclosed
WO-2024120853-A1	COMPOSITIONS COMPRISING SANGUISORBA OFFICINALIS ROOT EXTRACT AND USES THEREOF	CLARIANT INTERNATIONAL LTD (CH)	2024-06-13	—	—	WO	disclosed