Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24994279 | 1.00 | KMT2A (0.38) | KMT2AMEN1SCN10AHTTMGAM | |
| SCHEMBL27237651 | 1.00 | KMT2A (0.38) | KMT2AMEN1SCN10AHTTMGAM | |
| SCHEMBL30925917 | 0.88 | KMT2A (0.41) | KMT2AMEN1SCN10AHTTMGAM | |
| SCHEMBL24993565 | 0.88 | KMT2A (0.41) | KMT2AMEN1SCN10AHTTMGAM | |
| SCHEMBL29215025 | 0.88 | KMT2A (0.41) | KMT2AMEN1SCN10AHTTMGAM | |
| SCHEMBL30925907 | 0.84 | SCN10A (0.39) | KMT2AMEN1SCN10AHTTMGAM | |
| SCHEMBL24993542 | 0.84 | SCN10A (0.39) | KMT2AMEN1SCN10AHTTMGAM | |
| SCHEMBL29214962 | 0.84 | SCN10A (0.39) | KMT2AMEN1SCN10AHTTMGAM | |
| SCHEMBL24994264 | 0.82 | KMT2A (0.44) | KMT2AMEN1HTTMGAMMAPT | |
| SCHEMBL29215195 | 0.82 | KMT2A (0.44) | KMT2AMEN1HTTMGAMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076348-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118076348-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | disclosed |