Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24994264 | 0.90 | KMT2A (0.44) | MAPTKDM4EKMT2AMEN1POLB | |
| SCHEMBL29215195 | 0.90 | KMT2A (0.44) | MAPTKDM4EKMT2AMEN1POLB | |
| SCHEMBL30925917 | 0.87 | KMT2A (0.41) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL24993565 | 0.87 | KMT2A (0.41) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL29215025 | 0.87 | KMT2A (0.41) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL29215065 | 0.86 | KMT2A (0.41) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL24994261 | 0.86 | KMT2A (0.41) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL24994272 | 0.84 | TSHR (0.46) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL30925932 | 0.84 | TSHR (0.46) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL29214893 | 0.84 | TSHR (0.46) | MAPTKDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076348-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118076348-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | disclosed |