Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 6/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180433 | 1.00 | GRM4 (0.77) | GRM4HDAC6POLBGAAGPR27 | |
| SCHEMBL27181366 | 0.91 | GRM4 (0.74) | GRM4HDAC6POLBGAAGPR27 | |
| SCHEMBL30926458 | 0.91 | GRM4 (0.74) | GRM4HDAC6POLBGAAGPR27 | |
| SCHEMBL12197846 | 0.88 | GRM4 (0.85) | GRM4POLBGAAGPR27LMNA | |
| SCHEMBL12197830 | 0.87 | GRM4 (1.00) | GRM4GAAGPR27LMNATSHR | |
| SCHEMBL12197847 | 0.87 | GRM4 (0.76) | GRM4GAAGPR27LMNATSHR | |
| SCHEMBL12197843 | 0.84 | MAPT (0.74) | GRM4GAAGPR27LMNATSHR | |
| SCHEMBL12197879 | 0.84 | GRM4 (0.79) | GRM4POLBGPR27NPC1RAB9A | |
| SCHEMBL2530324 | 0.83 | GRM4 (1.00) | GRM4HDAC6KDRNPC1RAB9A | |
| SCHEMBL29496401 | 0.83 | GRM4 (1.00) | GRM4HDAC6KDRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | GRM4 4166/4885HDAC6 2738/4885POLB 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.