Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | TYK2 | P29597 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179653 | 1.00 | MEN1 (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL30926936 | 0.92 | KMT2A (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL27181139 | 0.92 | KMT2A (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL27180894 | 0.89 | MEN1 (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL27180089 | 0.88 | MAPT (0.76) | MEN1KMT2AALDH1A1PKMLMNA | |
| SCHEMBL30926701 | 0.88 | MAPT (0.76) | MEN1KMT2AALDH1A1PKMLMNA | |
| SCHEMBL2790669 | 0.85 | MEN1 (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL4258411 | 0.85 | MEN1 (0.92) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL30926711 | 0.85 | MEN1 (0.92) | MEN1KMT2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL13532168 | 0.85 | MEN1 (0.70) | MEN1KMT2AALDH1A1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | MEN1 4795/4885KMT2A 2544/4885ALDH1A1 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.