SCHEMBL30927751

SCHEMBL30927751

Cn1cc(-n2ccc3c(-c4nc(NC5CCCNC5)ncc4C(F)(F)F)c[nH]c3c2=O)cn1

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CCNK O75909 20/20 0.70
▸ CDK12 Q9NYV4 20/20 0.70
▸ CCNT1 O60563 18/20 0.70
▸ CDK9 P50750 18/20 0.70
▸ CDK7 P50613 6/20 0.70
▸ CCNH P51946 6/20 0.70
▸ MNAT1 P51948 4/20 0.70
▸ CCNE1 P24864 15/20 0.65
▸ CDK2 P24941 15/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31666667 1.00 CCNK (0.70) CCNKCDK12CCNT1CDK9CDK7
SCHEMBL31666854 0.90 CCNK (0.69) CCNKCDK12CCNT1CDK9CDK7
SCHEMBL30927600 0.90 CCNK (0.69) CCNKCDK12CCNT1CDK9CDK7
SCHEMBL31666803 0.89 CCNT1 (0.70) CCNKCDK12CCNT1CDK9CDK7
SCHEMBL31666794 0.89 CCNT1 (0.70) CCNKCDK12CCNT1CDK9CDK7
SCHEMBL30927703 0.88 CCNK (0.71) CCNKCDK12CCNT1CDK9CDK7
SCHEMBL31666726 0.88 CCNK (0.71) CCNKCDK12CCNT1CDK9CDK7
SCHEMBL29141592 0.88 CCNK (0.71) CCNKCDK12CCNT1CDK9CDK7
SCHEMBL31666750 0.88 CCNT1 (0.66) CCNKCDK12CCNT1CDK9CDK7
SCHEMBL31666833 0.88 CCNT1 (0.66) CCNKCDK12CCNT1CDK9CDK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137698-A1 CYCLIN-DEPENDENT KINASE 7 INHIBITORS JOINT STOCK CO «BIOCAD» (RU) 2026-05-21 — — US claimed
EP-4592283-A1 CYCLIN-DEPENDENT KINASE 7 INHIBITORS Joint Stock Company "Biocad" (RU) 2025-07-30 — — EP claimed
WO-2024063670-A1 CYCLIN-DEPENDENT KINASE 7 INHIBITORS Акционерное общество "БИОКАД" 2024-03-28 — — WO claimed
EP-4592283-A1 CYCLIN-DEPENDENT KINASE 7 INHIBITORS Joint Stock Company "Biocad" (RU) 2025-07-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137698-A1 CYCLIN-DEPENDENT KINASE 7 INHIBITORS CDK7, CDK6, CDK3 CCNK 13/4885CDK12 63/4885CCNT1 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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