SCHEMBL30929347

SCHEMBL30929347

CNC(=O)c1cn(C)c2ccc(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19657594 1.00 CREBBP (1.00) CREBBP
SCHEMBL19657415 0.88 CREBBP (1.00) CREBBP
SCHEMBL19657605 0.87 CREBBP (1.00) CREBBP
SCHEMBL19657414 0.86 CREBBP (1.00) CREBBP
SCHEMBL19657602 0.85 CREBBP (1.00) CREBBP
SCHEMBL19644307 0.85 CREBBP (1.00) CREBBP
SCHEMBL29704383 0.85 CREBBP (1.00) CREBBP
SCHEMBL19657608 0.85 CREBBP (1.00) CREBBP
SCHEMBL19657654 0.83 CREBBP (1.00) CREBBP
SCHEMBL25094215 0.83 CREBBP (0.77) CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4067347-B1 HETEROCYCLIC INHIBITORS OF CBP/EP300 FOR THE TREATMENT OF CANCER GENENTECH INC (US) 2024-06-19 EP disclosed