Coumachlor

Coumachlor

SCHEMBL30930052

CC(=O)CC(c1ccc(Cl)cc1)c1c(O)c2ccccc2oc1=O

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 10/20 0.84
VKORC1 Q9BQB6 3/20 0.84
ALB P02768 2/20 0.84
HSD17B10 Q99714 2/20 0.84
KDM4E B2RXH2 1/20 0.84
ALDH1A1 P00352 1/20 0.84
PCSK7 Q16549 1/20 0.84
MEN1 O00255 1/20 0.84
KMT2A Q03164 1/20 0.84
NR1I2 O75469 1/20 0.72
NR3C1 P04150 1/20 0.72
ADRA1A P35348 1/20 0.72
KCNH2 Q12809 1/20 0.72
NQO1 P15559 2/20 0.67
CYP3A4 P08684 1/20 0.63
BRD4 O60885 1/20 0.58
CRHBP P24387 1/20 0.57
CASP7 P55210 1/20 0.57
CASP6 P55212 1/20 0.57
CRHR2 Q13324 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumachlor SCHEMBL433455 1.00 CYP2C9 (0.84) CYP2C9VKORC1ALBHSD17B10KDM4E
Warfarin SCHEMBL3689 0.91 CYP2C9 (1.00) CYP2C9VKORC1ALBHSD17B10KDM4E
Warfarin SCHEMBL662875 0.91 CYP2C9 (1.00) CYP2C9VKORC1ALBHSD17B10KDM4E
Warfarin SCHEMBL2139452 0.91 CYP2C9 (1.00) CYP2C9VKORC1ALBHSD17B10KDM4E
Warfarin SCHEMBL4439794 0.91 CYP2C9 (1.00) CYP2C9VKORC1ALBHSD17B10KDM4E
Warfarin SCHEMBL3792087 0.91 CYP2C9 (1.00) CYP2C9VKORC1ALBHSD17B10KDM4E
Warfarin SCHEMBL29400364 0.91 CYP2C9 (1.00) CYP2C9VKORC1ALBHSD17B10KDM4E
SCHEMBL1649084 0.90 NQO1 (0.70) CYP2C9VKORC1ALBHSD17B10KDM4E
Warfarin SCHEMBL4757598 0.90 CYP2C9 (0.97) CYP2C9VKORC1ALBHSD17B10KDM4E
Warfarin SCHEMBL2597774 0.90 CYP2C9 (0.97) CYP2C9VKORC1ALBHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed