SCHEMBL30931887

SCHEMBL30931887

CN1CCN(c2ccc(Oc3cc(CO)cc(-c4cc(Cl)cc(Cl)c4)n3)cn2)CC1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 19/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21551681 1.00 FURIN (0.59) FURIN
SCHEMBL26077222 0.90 FURIN (0.54) FURIN
SCHEMBL21551781 0.89 FURIN (0.54) FURIN
SCHEMBL30931807 0.89 FURIN (0.54) FURIN
SCHEMBL21551142 0.88 FURIN (0.57) FURIN
SCHEMBL30931775 0.87 FURIN (0.68) FURIN
SCHEMBL21551385 0.87 FURIN (0.68) FURIN
SCHEMBL21551238 0.85 FURIN (0.55) FURIN
SCHEMBL30931806 0.85 FURIN (0.55) FURIN
SCHEMBL29890947 0.85 FURIN (0.55) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112384509-B Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2024-04-30 — — CN disclosed
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