Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 7/20 | 0.39 |
| ▸ | HTR2B | P41595 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30933677 | 0.99 | HTR2C (0.40) | PRMT5WDR77KCNH2CYP2D6GRIN2B | |
| Hydrochloric Acid SCHEMBL30933713 | 0.90 | HTR2C (0.45) | PRMT5WDR77KCNH2CYP2D6GRIN2B | |
| SCHEMBL30933715 | 0.86 | PRMT5 (0.46) | PRMT5WDR77CYP2D6HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL30933689 | 0.86 | PRMT5 (0.42) | PRMT5WDR77KCNH2CYP2D6GRIN2B | |
| Hydrochloric Acid SCHEMBL30933864 | 0.85 | PRMT5 (0.45) | PRMT5WDR77CYP2D6HTR2CHTR2B | |
| SCHEMBL30933924 | 0.81 | PRMT5 (0.42) | PRMT5WDR77KCNH2CYP2D6GRIN2B | |
| Hydrochloric Acid SCHEMBL30933664 | 0.80 | MAPK1 (0.44) | PRMT5WDR77KCNH2CYP2D6GRIN2B | |
| SCHEMBL30933772 | 0.79 | MAPT (0.52) | PRMT5WDR77CYP2D6HTR2CHTR2B | |
| SCHEMBL30933879 | 0.79 | KCNH2 (0.43) | PRMT5WDR77KCNH2CYP2D6GRIN2B | |
| Hydrochloric Acid SCHEMBL30933740 | 0.78 | HTR2A (0.44) | PRMT5WDR77KCNH2CYP2D6GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |