Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30933665 | 0.99 | CYP1A2 (0.47) | PRMT5WDR77CYP1A2CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL30933749 | 0.93 | CYP1A2 (0.48) | PRMT5WDR77CYP1A2CYP2D6SLC6A4 | |
| SCHEMBL30933772 | 0.88 | MAPT (0.52) | PRMT5WDR77CYP1A2CYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL30933684 | 0.88 | KDM4E (0.44) | PRMT5WDR77CYP1A2CYP2D6LMNA | |
| SCHEMBL30933844 | 0.87 | SLC6A4 (0.46) | PRMT5WDR77CYP1A2CYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL30933681 | 0.87 | MAPT (0.51) | PRMT5WDR77CYP1A2CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL30933656 | 0.86 | SLC6A4 (0.45) | PRMT5WDR77CYP1A2CYP2D6KDM4E | |
| SCHEMBL30933773 | 0.86 | CYP2D6 (0.56) | PRMT5WDR77CYP1A2CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL30933803 | 0.85 | CYP1A2 (0.58) | PRMT5WDR77CYP1A2CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL30933686 | 0.85 | PRMT5 (0.47) | PRMT5WDR77CYP1A2CYP2D6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |