Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 13/20 | 0.69 |
| ▸ | WNT1 | P04628 | 10/20 | 0.64 |
| ▸ | GSK3B | P49841 | 7/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.62 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.60 |
| ▸ | PLK4 | O00444 | 1/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.60 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.60 |
| ▸ | CDK1 | P06493 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | MARK3 | P27448 | 1/20 | 0.60 |
| ▸ | FLT4 | P35916 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.60 |
| ▸ | CDK8 | P49336 | 1/20 | 0.60 |
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23002840 | 1.00 | DYRK1A (0.69) | DYRK1AWNT1GSK3BKCNH2PRKAA1 | |
| SCHEMBL17096516 | 0.88 | DYRK1A (0.68) | DYRK1AWNT1GSK3BKCNH2PRKAA1 | |
| SCHEMBL21550495 | 0.85 | DYRK1A (0.74) | DYRK1AWNT1GSK3BKCNH2PRKAA1 | |
| SCHEMBL30933964 | 0.85 | DYRK1A (0.74) | DYRK1AWNT1GSK3BKCNH2PRKAA1 | |
| SCHEMBL17096798 | 0.85 | DYRK1A (0.79) | DYRK1AWNT1GSK3BKCNH2 | |
| SCHEMBL17095852 | 0.82 | DYRK1A (1.00) | DYRK1AWNT1GSK3BKCNH2 | |
| SCHEMBL23534215 | 0.82 | DYRK1A (0.67) | DYRK1AWNT1GSK3BKCNH2PRKAA1 | |
| SCHEMBL29754098 | 0.82 | DYRK1A (0.67) | DYRK1AWNT1GSK3BKCNH2PRKAA1 | |
| SCHEMBL17096509 | 0.81 | DYRK1A (0.90) | DYRK1AWNT1GSK3BKCNH2 | |
| SCHEMBL17095616 | 0.81 | DYRK1A (0.73) | DYRK1AWNT1GSK3BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112135821-B | 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors | 方济各安吉利克化学联合股份有限公司 | 2024-05-31 | — | — | CN | disclosed |