Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 12/20 | 0.75 |
| ▸ | EPAS1 | Q99814 | 17/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | ARNT | P27540 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933804 | 1.00 | VEGFA (0.75) | VEGFAEPAS1CYP2C9ARNTCYP2C19 | |
| SCHEMBL21005370 | 1.00 | VEGFA (0.75) | VEGFAEPAS1CYP2C9ARNTCYP2C19 | |
| SCHEMBL21005012 | 1.00 | VEGFA (0.75) | VEGFAEPAS1CYP2C9ARNTCYP2C19 | |
| SCHEMBL18688486 | 0.90 | VEGFA (0.72) | VEGFAEPAS1CYP2C9ARNTCYP2C19 | |
| SCHEMBL30933849 | 0.90 | VEGFA (0.65) | VEGFAEPAS1 | |
| SCHEMBL30933799 | 0.89 | EPAS1 (0.67) | VEGFAEPAS1CYP2C9ARNTCYP2C19 | |
| SCHEMBL18688469 | 0.89 | VEGFA (0.71) | VEGFAEPAS1CYP2C9ARNTCYP2C19 | |
| SCHEMBL21005085 | 0.89 | VEGFA (0.71) | VEGFAEPAS1CYP2C9ARNTCYP2C19 | |
| SCHEMBL21004945 | 0.87 | EPAS1 (0.68) | VEGFAEPAS1CYP2C9ARNTCYP2C19 | |
| SCHEMBL18688614 | 0.87 | EPAS1 (0.69) | VEGFAEPAS1CYP2C9ARNTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619386-A1 | ARYL THIOETHERS AS HIF-2ALPHA INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024104932-A1 | ARYL THIOETHERS AS HIF-2ALPHA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-23 | — | — | WO | disclosed |