Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 8/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 5/20 | 0.43 |
| ▸ | TDP2 | O95551 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30935140 | 0.89 | MAPKAPK2 (0.53) | MAPKAPK2MAPK9PARP10PARP11TDP2 | |
| SCHEMBL30935080 | 0.88 | MAPKAPK2 (0.55) | MAPKAPK2MAPK9PARP10PARP11TDP2 | |
| SCHEMBL30934991 | 0.88 | MAPKAPK2 (0.66) | MAPKAPK2MAPK9PARP10PARP11TDP2 | |
| SCHEMBL30935237 | 0.88 | MAPKAPK2 (0.52) | MAPKAPK2MAPK9PARP10PARP11TDP2 | |
| SCHEMBL30935410 | 0.88 | MAPKAPK2 (0.52) | MAPKAPK2MAPK9PARP10PARP11TDP2 | |
| SCHEMBL30935065 | 0.87 | MAPKAPK2 (0.54) | MAPKAPK2MAPK9PARP10PARP11TDP2 | |
| SCHEMBL30935061 | 0.87 | MAPKAPK2 (0.51) | MAPKAPK2MAPK9PARP10PARP11TDP2 | |
| SCHEMBL30935281 | 0.86 | MAPKAPK2 (0.53) | MAPKAPK2MAPK9PARP10PARP11TDP2 | |
| SCHEMBL30935370 | 0.85 | MAPKAPK2 (0.52) | MAPKAPK2MAPK9PARP10PARP11TDP2 | |
| SCHEMBL30935292 | 0.85 | MAPKAPK2 (0.50) | MAPKAPK2MAPK9PARP10PARP11TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |