Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27338224 | 0.88 | KIT (0.78) | KIT | |
| SCHEMBL14758772 | 0.86 | KIT (0.64) | KIT | |
| SCHEMBL30935688 | 0.86 | KIT (0.72) | KIT | |
| SCHEMBL27338531 | 0.86 | KIT (0.74) | KIT | |
| SCHEMBL27334423 | 0.86 | KIT (0.74) | KIT | |
| SCHEMBL27334700 | 0.86 | KIT (0.74) | KIT | |
| SCHEMBL27334596 | 0.86 | KIT (0.71) | KIT | |
| SCHEMBL14740064 | 0.86 | KIT (0.63) | KIT | |
| SCHEMBL27336999 | 0.85 | KIT (0.73) | KIT | |
| Labuxtinib SCHEMBL24508232 | 0.85 | KIT (1.00) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630424-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | Third Harmonic Bio, Inc. (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024124002-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | THIRD HARMONIC BIO, INC. (US) | 2024-06-13 | — | — | WO | disclosed |