SCHEMBL30935563

SCHEMBL30935563

COc1ccn2c(C(=O)Nc3cc(-c4noc(CC5CCCCO5)n4)ccc3C)cnc2c1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30935587 0.98 KIT (0.65) KIT
SCHEMBL30935718 0.91 KIT (0.67) KIT
SCHEMBL30935573 0.89 KIT (0.68) KIT
SCHEMBL14740208 0.88 KIT (0.81) KIT
SCHEMBL30935651 0.88 KIT (0.68) KIT
SCHEMBL30935681 0.88 KIT (0.66) KIT
SCHEMBL27336084 0.86 KIT (0.66) KIT
SCHEMBL14740377 0.86 KIT (0.83) KIT
SCHEMBL27336153 0.86 KIT (0.69) KIT
SCHEMBL27336244 0.85 KIT (0.62) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630424-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS Third Harmonic Bio, Inc. (US) 2025-10-15 EP disclosed
WO-2024124002-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS THIRD HARMONIC BIO, INC. (US) 2024-06-13 WO disclosed