SCHEMBL30935577

SCHEMBL30935577

Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2cc(COCC(C)(C)O)ccn12

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14738773 0.92 KIT (1.00) KIT
SCHEMBL27336632 0.90 KIT (0.82) KIT
SCHEMBL30935517 0.89 KIT (0.74) KIT
SCHEMBL27336426 0.89 KIT (0.84) KIT
SCHEMBL30964076 0.89 KIT (0.70) KIT
SCHEMBL14738442 0.86 KIT (1.00) KIT
SCHEMBL14738943 0.85 KIT (1.00) KIT
SCHEMBL27336245 0.84 KIT (0.87) KIT
SCHEMBL14738950 0.84 KIT (1.00) KIT
SCHEMBL14756677 0.84 KIT (0.85) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630424-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS Third Harmonic Bio, Inc. (US) 2025-10-15 EP disclosed
WO-2024124002-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS THIRD HARMONIC BIO, INC. (US) 2024-06-13 WO disclosed