Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936935 | 0.90 | EGFR (0.54) | EGFRALKPTK2 | |
| SCHEMBL30936255 | 0.88 | EGFR (0.54) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL30936237 | 0.86 | EGFR (0.51) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL30936192 | 0.85 | EGFR (0.52) | EGFRALKPTK2 | |
| SCHEMBL30936231 | 0.84 | EGFR (0.54) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL30936363 | 0.84 | EGFR (0.46) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL30936897 | 0.84 | EGFR (0.50) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL30936877 | 0.84 | EGFR (0.50) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL30936283 | 0.84 | EGFR (0.51) | EGFRALKPTK2 | |
| SCHEMBL30936224 | 0.84 | EGFR (0.53) | EGFRALKINSRIGF1RPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | claimed |
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |