SCHEMBL30936779

SCHEMBL30936779

CCc1cc(Nc2ncc(Cl)c(Nc3ccc4nccnc4c3NS(C)(=O)=O)n2)c(OC)cc1N1CCC(N(C)CCC(=O)OC(C)(C)C)CC1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30936802 0.94 EGFR (0.59) EGFR
SCHEMBL30936863 0.91 EGFR (0.59) EGFR
SCHEMBL27076072 0.89 EGFR (0.68) EGFR
SCHEMBL30937081 0.85 EGFR (0.65) EGFR
SCHEMBL30936825 0.85 EGFR (0.60) EGFR
SCHEMBL27076087 0.85 EGFR (0.62) EGFR
SCHEMBL30936793 0.84 EGFR (0.60) EGFR
SCHEMBL30936902 0.84 EGFR (0.59) EGFR
SCHEMBL27076047 0.83 EGFR (0.65) EGFR
SCHEMBL30015471 0.83 EGFR (0.63) EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024072178-A1 COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF (주)사이러스테라퓨틱스 2024-04-04 — — WO disclosed
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