Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.66 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.47 |
| ▸ | INSR | P06213 | 2/20 | 0.47 |
| ▸ | IGF1R | P08069 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27076139 | 0.94 | EGFR (0.68) | EGFRMETALKINSRIGF1R | |
| SCHEMBL26378902 | 0.93 | EGFR (0.68) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30015178 | 0.93 | EGFR (0.68) | EGFRMETALKINSRIGF1R | |
| SCHEMBL25788995 | 0.93 | EGFR (0.57) | EGFR | |
| SCHEMBL31204414 | 0.93 | EGFR (0.67) | EGFR | |
| SCHEMBL27075954 | 0.93 | EGFR (0.66) | EGFRMETALKINSRIGF1R | |
| SCHEMBL26380124 | 0.93 | EGFR (0.67) | EGFR | |
| SCHEMBL27076101 | 0.90 | EGFR (0.63) | EGFRMETALKINSRIGF1R | |
| SCHEMBL27076042 | 0.90 | EGFR (0.64) | EGFRMETALKINSRIGF1R | |
| SCHEMBL26379415 | 0.90 | EGFR (0.69) | EGFRALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |