Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.64 |
| ▸ | IKZF3 | Q9UKT9 | 14/20 | 0.64 |
| ▸ | TNF | P01375 | 7/20 | 0.57 |
| ▸ | IL1B | P01584 | 4/20 | 0.57 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20427477 | 0.87 | CRBN (0.68) | CRBNIKZF3TNFIL1BIKZF1 | |
| SCHEMBL2248358 | 0.87 | CRBN (0.68) | CRBNIKZF3TNFIL1BIKZF1 | |
| SCHEMBL12372115 | 0.87 | CRBN (0.68) | CRBNIKZF3TNFIL1BIKZF1 | |
| SCHEMBL22959737 | 0.87 | CRBN (0.70) | CRBNIKZF3TNFIL1BIKZF1 | |
| SCHEMBL26366259 | 0.87 | CRBN (0.70) | CRBNIKZF3TNFIL1BIKZF1 | |
| SCHEMBL2250436 | 0.86 | CRBN (0.58) | CRBNIKZF3TNFIL1BIKZF1 | |
| SCHEMBL29790775 | 0.86 | CRBN (0.58) | CRBNIKZF3TNFIL1BIKZF1 | |
| SCHEMBL2252814 | 0.86 | CRBN (0.69) | CRBNIKZF3TNFIL1BIKZF1 | |
| SCHEMBL19849551 | 0.86 | CRBN (0.57) | CRBNIKZF3TNFIL1BIKZF1 | |
| SCHEMBL2251635 | 0.85 | CRBN (0.66) | CRBNIKZF3TNFIL1BIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |