SCHEMBL30937396

SCHEMBL30937396

C=CC[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)n(C(=O)c2ccccc2)c1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 3/20 0.37
SLC28A1 O00337 1/20 0.36
SLC28A2 O43868 1/20 0.36
SLC29A1 Q99808 1/20 0.36
SLC28A3 Q9HAS3 1/20 0.36
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
MTOR P42345 1/20 0.35
MDM2 Q00987 1/20 0.35
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
MAPT P10636 1/20 0.35
CDA P32320 1/20 0.35
P2RY2 P41231 2/20 0.34
P2RY4 P51582 2/20 0.34
CYP1A2 P05177 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LGALS9 O00182 2/20 0.33
LGALS1 P09382 2/20 0.33
LGALS3 P17931 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30937398 0.87 P2RY6 (0.39) P2RY6SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30937390 0.85 P2RY6 (0.38) P2RY6SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30937402 0.84 P2RY6 (0.37) P2RY6SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30937387 0.84 P2RY6 (0.41) P2RY6SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30937386 0.83 P2RY6 (0.40) P2RY6SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30937384 0.83 P2RY6 (0.40) P2RY6SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL30937407 0.82 P2RY6 (0.32) P2RY6P2RY2P2RY4
SCHEMBL30937404 0.82 P2RY6 (0.32) P2RY6P2RY2P2RY4
SCHEMBL31543030 0.80 P2RY6 (0.35) P2RY6P2RY2P2RY4
SCHEMBL30937412 0.80 P2RY6 (0.32) P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025060642-A1 MODIFIED NUCLEOTIDE COMPOUND, OLIGONUCLEOTIDE THEREOF, AND USE THEREOF 广州必贝特医药股份有限公司 2025-03-27 WO disclosed
CN-118063533-B Modified nucleotide compound, oligonucleotide and application thereof 广州必贝特医药股份有限公司 2024-08-27 CN disclosed
CN-118063533-A Modified nucleotide compound, oligonucleotide and application thereof 广州必贝特医药股份有限公司 2024-05-24 CN disclosed