Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 10/20 | 0.78 |
| ▸ | CLK1 | P49759 | 9/20 | 0.78 |
| ▸ | KIF20A | O95235 | 10/20 | 0.74 |
| ▸ | CLK2 | P49760 | 2/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.64 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.64 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.64 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2711278 | 1.00 | DYRK1A (0.78) | DYRK1ACLK1KIF20ACLK2CLK4 | |
| SCHEMBL2711280 | 1.00 | DYRK1A (0.78) | DYRK1ACLK1KIF20ACLK2CLK4 | |
| SCHEMBL19192706 | 0.88 | DYRK1A (0.60) | DYRK1ACLK1KIF20ACLK2CLK4 | |
| SCHEMBL19192548 | 0.87 | DYRK1A (0.76) | DYRK1ACLK1KIF20ACLK2CLK4 | |
| SCHEMBL2725098 | 0.87 | DYRK1A (0.76) | DYRK1ACLK1KIF20ACLK2CLK4 | |
| SCHEMBL2725265 | 0.87 | DYRK1A (0.76) | DYRK1ACLK1KIF20ACLK2CLK4 | |
| SCHEMBL2726304 | 0.87 | DYRK1A (1.00) | DYRK1ACLK1KIF20ACLK2CLK4 | |
| SCHEMBL2726290 | 0.87 | DYRK1A (1.00) | DYRK1ACLK1KIF20ACLK2CLK4 | |
| SCHEMBL2725264 | 0.87 | DYRK1A (0.76) | DYRK1ACLK1KIF20ACLK2CLK4 | |
| SCHEMBL2726292 | 0.87 | DYRK1A (1.00) | DYRK1ACLK1KIF20ACLK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4629988-A1 | DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER AND INFECTIONS | Centre National de la Recherche Scientifique (FR) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121072-A1 | DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER AND INFECTIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-06-13 | — | — | WO | disclosed |