Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.62 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.51 |
| ▸ | IRAK3 | Q9Y616 | 2/20 | 0.51 |
| ▸ | CCNC | P24863 | 1/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.51 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.51 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.49 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26814219 | 1.00 | CRBN (0.62) | CRBNIRAK1IRAK4IRAK3CCNC | |
| SCHEMBL26815469 | 0.95 | CRBN (0.60) | CRBNIRAK1IRAK4IRAK3CCNC | |
| SCHEMBL26815047 | 0.95 | CRBN (0.60) | CRBNIRAK1IRAK4IRAK3CCNC | |
| SCHEMBL26814209 | 0.92 | CRBN (0.65) | CRBNIRAK1IRAK4IRAK3CCNC | |
| SCHEMBL22940923 | 0.91 | CRBN (0.67) | CRBNIRAK1IRAK4IRAK3CCNC | |
| SCHEMBL26815056 | 0.90 | CRBN (0.58) | CRBNIRAK1IRAK4IRAK3CCNC | |
| SCHEMBL26815070 | 0.89 | CRBN (0.57) | CRBNIRAK1IRAK4IRAK3CCNC | |
| SCHEMBL26814133 | 0.89 | CRBN (0.71) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL26815117 | 0.89 | CRBN (0.63) | CRBNIRAK1IRAK4IRAK3CCNC | |
| SCHEMBL26815156 | 0.87 | CRBN (0.61) | CRBNIRAK1IRAK4IRAK3CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076607-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |