Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ESRRB | O95718 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESRRA | P11474 | 1/20 | 0.30 |
| ▸ | ESRRG | P62508 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1981909 | 1.00 | ELANE (0.32) | ELANESSTR4GRM2TRPV4NPSR1 | |
| SCHEMBL1979583 | 0.90 | ELANE (0.33) | ELANESSTR4GRM2NPSR1 | |
| SCHEMBL29437994 | 0.90 | ELANE (0.33) | ELANESSTR4GRM2NPSR1 | |
| SCHEMBL30939565 | 0.88 | SLC6A4 (0.33) | NPSR1 | |
| SCHEMBL1981385 | 0.88 | SLC6A4 (0.33) | NPSR1 | |
| SCHEMBL21610173 | 0.81 | ELANE (0.32) | ELANE | |
| SCHEMBL24350320 | 0.81 | CYP11B1 (0.31) | — | |
| SCHEMBL21580651 | 0.80 | ELANE (0.33) | ELANEGRM2CYP2C9 | |
| SCHEMBL31089782 | 0.80 | ELANE (0.33) | ELANEGRM2CYP2C9 | |
| SCHEMBL19805308 | 0.79 | SSTR4 (0.32) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118267386-A | Modulators of KV3 channels for the treatment of pain | 奥提芙尼治疗学有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-108472288-B | Modulators of KV3 channels for the treatment of pain | 奥提芙尼治疗学有限公司 | 2024-05-28 | — | — | CN | disclosed |