Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940599 | 1.00 | USP2 (0.58) | USP2CYP3A4SMN1; SMN2FFAR4MEN1 | |
| SCHEMBL5808428 | 1.00 | USP2 (0.58) | USP2CYP3A4SMN1; SMN2FFAR4MEN1 | |
| SCHEMBL15365231 | 0.98 | USP2 (0.56) | USP2CYP3A4SMN1; SMN2FFAR4MEN1 | |
| SCHEMBL5606115 | 0.91 | FFAR4 (0.48) | USP2CYP3A4SMN1; SMN2FFAR4MEN1 | |
| SCHEMBL5606111 | 0.91 | FFAR4 (0.48) | USP2CYP3A4SMN1; SMN2FFAR4MEN1 | |
| SCHEMBL10616236 | 0.89 | USP2 (0.55) | USP2CYP3A4SMN1; SMN2FFAR4MEN1 | |
| SCHEMBL15027439 | 0.89 | USP2 (0.69) | USP2CYP3A4SMN1; SMN2FFAR4MEN1 | |
| SCHEMBL10081318 | 0.87 | USP2 (0.65) | USP2CYP3A4SMN1; SMN2FFAR4MEN1 | |
| SCHEMBL23789287 | 0.82 | FFAR1 (0.67) | FFAR4FFAR1GPR84NFKB1 | |
| SCHEMBL865728 | 0.82 | FFAR1 (0.67) | FFAR4FFAR1GPR84NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118369427-A | Extrahepatic delivery IRNA compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118369427-A | Extrahepatic delivery IRNA compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2024-07-19 | — | — | CN | disclosed |