Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.56 |
| ▸ | WIZ | O95785 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27302560 | 1.00 | IKZF2 (0.56) | IKZF2CRBNWIZCSNK1A1ESR1 | |
| SCHEMBL24501883 | 0.98 | CRBN (0.58) | IKZF2CRBNWIZCSNK1A1ESR1 | |
| SCHEMBL20372613 | 0.98 | CRBN (0.58) | IKZF2CRBNWIZCSNK1A1ESR1 | |
| SCHEMBL29648403 | 0.98 | CRBN (0.58) | IKZF2CRBNWIZCSNK1A1ESR1 | |
| Hydrochloric Acid SCHEMBL31181025 | 0.97 | CRBN (0.57) | IKZF2CRBNWIZCSNK1A1ESR1 | |
| SCHEMBL27302539 | 0.94 | CRBN (0.54) | IKZF2CRBNWIZCSNK1A1ESR1 | |
| SCHEMBL30942236 | 0.94 | CRBN (0.54) | IKZF2CRBNWIZCSNK1A1ESR1 | |
| SCHEMBL27424055 | 0.93 | IKZF2 (0.56) | IKZF2CRBNWIZCSNK1A1ESR1 | |
| SCHEMBL20235035 | 0.93 | CRBN (0.56) | IKZF2CRBNWIZCSNK1A1ESR1 | |
| Hydrochloric Acid SCHEMBL29264348 | 0.91 | CRBN (0.57) | IKZF2CRBNWIZCSNK1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626554-A1 | GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | Tiger Biotherapeutics Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118960-A1 | GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | TIGER BIOTHERAPEUTICS INC. (US) | 2024-06-06 | — | — | WO | disclosed |