Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.56 |
| ▸ | WNT3A | P56704 | 1/20 | 0.53 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520278 | 1.00 | DYRK1A (0.65) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28520304 | 0.99 | DYRK1A (0.64) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30944335 | 0.99 | DYRK1A (0.64) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30944394 | 0.89 | DYRK1A (0.61) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28523776 | 0.89 | DYRK1A (0.61) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30944343 | 0.89 | DYRK1A (0.69) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28521697 | 0.89 | DYRK1A (0.69) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30944395 | 0.88 | DYRK1A (0.67) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30944408 | 0.88 | DYRK1A (0.67) | DYRK1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28522297 | 0.88 | DYRK1A (0.67) | DYRK1AHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |