SCHEMBL30944747

SCHEMBL30944747

C[C@H](O)c1ccc(C(=O)Nc2ccccc2NC(=O)OC(C)(C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NAMPT P43490 1/20 0.45
HDAC1 Q13547 6/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GLA P06280 1/20 0.44
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HDAC3 O15379 3/20 0.43
HDAC2 Q92769 3/20 0.43
NCOR2 Q9Y618 3/20 0.43
MAPT P10636 2/20 0.42
RECQL P46063 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27406952 1.00 F10 (0.48) F10MEN1KMT2ANAMPTHDAC1
SCHEMBL30944753 1.00 F10 (0.48) F10MEN1KMT2ANAMPTHDAC1
SCHEMBL12934078 0.86 F10 (0.45) F10MEN1KMT2ANAMPTHDAC1
SCHEMBL12934079 0.86 F10 (0.45) F10MEN1KMT2ANAMPTHDAC1
SCHEMBL1753693 0.86 MEN1 (0.48) F10MEN1KMT2ANAMPTHDAC1
SCHEMBL1061093 0.85 HDAC1 (0.46) F10MEN1KMT2ANAMPTHDAC1
SCHEMBL2829176 0.84 POLB (0.56) F10MEN1KMT2ANAMPTHDAC1
SCHEMBL12772560 0.83 NPC1 (0.57) F10MEN1KMT2ANAMPTHDAC1
SCHEMBL1066788 0.83 F10 (0.53) F10MEN1KMT2ANAMPTHDAC1
SCHEMBL13949629 0.83 MEN1 (0.54) F10MEN1KMT2ANAMPTHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4629984-A1 DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS BioVentures, LLC (US) 2025-10-15 EP disclosed
WO-2024123929-A1 DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS BIOVENTURES, LLC (US) 2024-06-13 WO disclosed