SCHEMBL30944770

SCHEMBL30944770

Cc1cc(-n2nc3c(c2-n2ccn(-c4ccc5c(cnn5C)c4F)c2=O)[C@H](C)NCC3)cc(C)c1F

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31347769 1.00 GLP1R (0.49) GLP1R
SCHEMBL21183758 1.00 GLP1R (0.49) GLP1R
SCHEMBL31347770 1.00 GLP1R (0.49) GLP1R
Hydrochloric Acid SCHEMBL29129763 0.99 GLP1R (0.49) GLP1R
Hydrochloric Acid SCHEMBL21175298 0.99 GLP1R (0.49) GLP1R
Hydrochloric Acid SCHEMBL31011042 0.99 GLP1R (0.49) GLP1R
Hydrochloric Acid SCHEMBL31011029 0.99 GLP1R (0.49) GLP1R
SCHEMBL31616874 0.96 GLP1R (0.47) GLP1R
SCHEMBL31692579 0.95 GLP1R (0.48) GLP1R
SCHEMBL31616853 0.95 GLP1R (0.46) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552158-A Preparation method of GLP-1 receptor agonist Orforglipron 河南省科学院化学研究所 2025-03-04 — — CN claimed
EP-4638421-A1 PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR Eli Lilly and Company (US) 2025-10-29 — — EP disclosed
CN-120136870-A GLP-1 receptor targeting compounds and uses thereof 信达生物科技有限公司 2025-06-13 — — CN disclosed
WO-2025119206-A1 GLP-1 RECEPTOR TARGETING COMPOUNDS AND USES THEREOF FORTVITA BIOLOGICS INC. (KY) 2025-06-12 — — WO disclosed
CN-119431365-A Phenyl heterocyclic derivative-containing regulator and preparation method and application thereof 江苏豪森药业集团有限公司 2025-02-14 — — CN disclosed
WO-2024137426-A1 PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR ELI LILLY AND COMPANY (US) 2024-06-27 — — WO disclosed
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