Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.65 |
| ▸ | SRC | P12931 | 6/20 | 0.65 |
| ▸ | KIT | P10721 | 4/20 | 0.65 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.65 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.65 |
| ▸ | EGFR | P00533 | 2/20 | 0.65 |
| ▸ | LCK | P06239 | 2/20 | 0.65 |
| ▸ | FYN | P06241 | 2/20 | 0.65 |
| ▸ | CSF1R | P07333 | 2/20 | 0.65 |
| ▸ | YES1 | P07947 | 2/20 | 0.65 |
| ▸ | LYN | P07948 | 2/20 | 0.65 |
| ▸ | RET | P07949 | 2/20 | 0.65 |
| ▸ | HCK | P08631 | 2/20 | 0.65 |
| ▸ | BCR | P11274 | 2/20 | 0.65 |
| ▸ | BRAF | P15056 | 2/20 | 0.65 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.65 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.65 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.65 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.65 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704785 | 0.94 | ABL1 (0.65) | ABL1SRCKITPKMYT1EPHB6 | |
| SCHEMBL30197903 | 0.94 | ABL1 (0.65) | ABL1SRCKITPKMYT1EPHB6 | |
| SCHEMBL29381575 | 0.94 | ABL1 (0.65) | ABL1SRCKITPKMYT1EPHB6 | |
| SCHEMBL1704413 | 0.92 | ABL1 (0.64) | ABL1SRCKITPKMYT1EPHB6 | |
| SCHEMBL1704880 | 0.87 | ABL1 (0.64) | ABL1SRCKITPKMYT1EPHB6 | |
| SCHEMBL1704263 | 0.86 | SIK1 (0.56) | ABL1SRCKITPKMYT1EPHB6 | |
| SCHEMBL1704743 | 0.86 | ABL1 (0.54) | ABL1SRCKITPKMYT1EPHB6 | |
| SCHEMBL31634943 | 0.86 | PKMYT1 (0.79) | ABL1SRCKITPKMYT1EPHB6 | |
| SCHEMBL14416602 | 0.86 | PKMYT1 (0.79) | ABL1SRCKITPKMYT1EPHB6 | |
| SCHEMBL29249184 | 0.85 | ABL1 (0.52) | ABL1SRCKITPKMYT1EPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4629981-A2 | SMALL MOLECULE DEGRADERS OF C-SRC KINASE | The Regents Of The University Of Michigan (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024123819-A2 | SMALL MOLECULE DEGRADERS OF C-SRC KINASE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-13 | — | — | WO | disclosed |