⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22219448 | 0.67 | — | — | |
| SCHEMBL19823681 | 0.64 | — | — | |
| SCHEMBL11005241 | 0.63 | — | — | |
| SCHEMBL1338275 | 0.62 | — | — | |
| SCHEMBL13110697 | 0.60 | — | — | |
| SCHEMBL963635 | 0.60 | — | — | |
| SCHEMBL19663867 | 0.60 | — | — | |
| SCHEMBL1172952 | 0.59 | — | — | |
| SCHEMBL24871 | 0.59 | — | — | |
| SCHEMBL14498529 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084677-A | Method for continuously preparing tetrafluoroethyl-N, N-dimethylamine | 江西中氟化学材料科技股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-109627165-B | Method for co-production of 2-fluoropropionate and ethyl difluoroacetate | 浙江巨化技术中心有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-111116427-B | Preparation method of fluorosulfonyl tetrafluoroethyl (trifluoroethylene) ether | 浙江巨化技术中心有限公司 | 2022-05-27 | — | — | CN | claimed |
| EP-3498695-B1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID | ZHEJIANG YONGTAI TECHNOLOGY CO LTD (CN) | 2020-12-09 | — | — | EP | claimed |
| CN-111116427-A | Preparation method of fluorosulfonyl tetrafluoroethyl (trifluoroethylene) ether | 浙江巨化技术中心有限公司 | 2020-05-08 | — | — | CN | claimed |
| US-10556868-B2 | Method for synthesizing 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid and intermediates thereof | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2020-02-11 | — | — | US | claimed |
| US-20190202791-A1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID AND INTERMEDIATES THEREOF | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2019-07-04 | — | — | US | claimed |
| EP-3498695-A1 | METHOD FOR SYNTHESIZING 3-(DIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID, AND INTERMEDIATES THEREOF | Zhejiang Yongtai Technology Co., Ltd. (CN) | 2019-06-19 | — | — | EP | claimed |
| CN-109627165-A | A kind of method of coproduction 2- fluorine propionic ester and ethyl difluoro | 浙江巨化技术中心有限公司 | 2019-04-16 | — | — | CN | claimed |
| EP-2089351-B1 | STEREOSELECTIVE ONE STEP FLUORINATION PROCESS FOR THE PREPARATION OF 2-FLUOROPROPIONATE | BAYER IP GMBH (DE) | 2017-01-25 | — | — | EP | claimed |
| US-8093421-B2 | Stereoselective one step fluorination process for the preparation of 2-flouropropionate | BAYER CROPSCIENCE AG (DE) | 2012-01-10 | — | — | US | claimed |
| US-20100069663-A1 | STEREOSELECTIVE ONE STEP FLUORINATION PROCESS FOR THE PREPARATION OF 2-FLOUROPROPIONATE | MICHELIN RECHERCHE ET TECHNIQUE, S.A (CH) | 2010-03-18 | — | — | US | claimed |
| EP-2089351-A1 | STEREOSELECTIVE ONE STEP FLUORINATION PROCESS FOR THE PREPARATION OF 2-FLUOROPROPIONATE | Bayer CropScience AG (DE) | 2009-08-19 | — | — | EP | claimed |
| WO-2008049531-A1 | STEREOSELECTIVE ONE STEP FLUORINATION PROCESS FOR THE PREPARATION OF 2-FLUOROPROPIONATE | BAYER CROPSCIENCE AG (DE) | 2008-05-02 | — | — | WO | claimed |
| CN-120117983-A | Method for preparing optically active methyl 2- (R) -fluoropropionate | 山东国邦药业有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-119462508-A | 3-Fluoroalkyl-full substituted pyrazole compound and preparation method thereof | 西北师范大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-118515558-A | Method for preparing optically active methyl fluoropropionate by using diethylamino sulfur trifluoride | 福建永晶科技股份有限公司 | 2024-08-20 | — | — | CN | disclosed |
| EP-2089351-A1 | STEREOSELECTIVE ONE STEP FLUORINATION PROCESS FOR THE PREPARATION OF 2-FLUOROPROPIONATE | Bayer CropScience AG (DE) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008152138-A2 | METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008049531-A1 | STEREOSELECTIVE ONE STEP FLUORINATION PROCESS FOR THE PREPARATION OF 2-FLUOROPROPIONATE | BAYER CROPSCIENCE AG (DE) | 2008-05-02 | — | — | WO | disclosed |