SCHEMBL30945374

SCHEMBL30945374

O=C(N[C@@H](CCC1CCCCC1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.52
TP53 P04637 3/20 0.52
TLR2 O60603 2/20 0.50
MDM2 Q00987 7/20 0.49
CASP3 P42574 2/20 0.48
FDFT1 P37268 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945367 1.00 MDM4 (0.52) MDM4TP53TLR2MDM2CASP3
SCHEMBL20356921 1.00 MDM4 (0.52) MDM4TP53TLR2MDM2CASP3
SCHEMBL22442043 1.00 MDM4 (0.52) MDM4TP53TLR2MDM2CASP3
SCHEMBL30945373 1.00 MDM4 (0.52) MDM4TP53TLR2MDM2CASP3
SCHEMBL30945372 1.00 MDM4 (0.52) MDM4TP53TLR2MDM2CASP3
SCHEMBL20356919 1.00 MDM4 (0.52) MDM4TP53TLR2MDM2CASP3
SCHEMBL25356638 0.99 MDM4 (0.53) MDM4TP53TLR2MDM2CASP3
SCHEMBL25356643 0.99 MDM4 (0.53) MDM4TP53TLR2MDM2CASP3
SCHEMBL25356844 0.97 MDM4 (0.53) MDM4TP53TLR2MDM2CASP3
SCHEMBL25356848 0.97 MDM4 (0.53) MDM4TP53TLR2MDM2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049101-A1 TOPICAL TREATMENT OF SKIN CANCER USING OLIGOPEPTIDES BACOBA AG (CH) 2026-02-19 US disclosed
US-20240174714-A1 TREATMENT OF SKIN DISORDERS BACOBA AG (CH) 2024-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174714-A1 TREATMENT OF SKIN DISORDERS HRH4, NR1H4, NR1H3 MDM4 3823/4885TP53 4245/4885TLR2 619/4885
US-20260049101-A1 TOPICAL TREATMENT OF SKIN CANCER USING OLIGOPEPTIDES NGLY1, MC1R, EGFR MDM4 2280/4885TP53 190/4885TLR2 559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.