Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29726716 | 0.90 | CHRM2 (0.47) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 | |
| SCHEMBL19250570 | 0.90 | CHRM2 (0.47) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 | |
| SCHEMBL27224503 | 0.88 | CHRM2 (0.39) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 | |
| SCHEMBL15483937 | 0.86 | CHRM2 (0.43) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 | |
| SCHEMBL17243890 | 0.81 | CHRM2 (0.46) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 | |
| SCHEMBL30849529 | 0.81 | CHRM2 (0.47) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 | |
| SCHEMBL417319 | 0.81 | CHRM2 (0.47) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 | |
| SCHEMBL24983235 | 0.80 | DPP4 (0.36) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 | |
| SCHEMBL5422531 | 0.80 | CHRM2 (0.42) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 | |
| SCHEMBL9967101 | 0.80 | CHRM2 (0.42) | CHRM2CHRM4CHRM3CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947679-B | Synthesis method of 6, 6-dimethyl-3-hetero-nitrogen-bicyclo [3.1.0] hexane-2-carboxylic acid methyl ester | 杭州澳赛诺生物科技有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-115947679-B | Synthesis method of 6, 6-dimethyl-3-hetero-nitrogen-bicyclo [3.1.0] hexane-2-carboxylic acid methyl ester | 杭州澳赛诺生物科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-115947679-B | Synthesis method of 6, 6-dimethyl-3-hetero-nitrogen-bicyclo [3.1.0] hexane-2-carboxylic acid methyl ester | 杭州澳赛诺生物科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-115947679-B | Synthesis method of 6, 6-dimethyl-3-hetero-nitrogen-bicyclo [3.1.0] hexane-2-carboxylic acid methyl ester | 杭州澳赛诺生物科技有限公司 | 2024-06-07 | — | — | CN | disclosed |