Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | FRK | P42685 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112056 | 0.91 | MAPK14 (0.51) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL10290368 | 0.90 | CSNK1D (0.53) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL3109802 | 0.90 | ACVR1 (0.49) | MAPK14MAPK13MAPK12MAPK11THRB | |
| SCHEMBL10290363 | 0.87 | CSNK1D (0.51) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL10290856 | 0.86 | CSNK1D (0.54) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL3107825 | 0.85 | CSNK1D (0.49) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL3108242 | 0.85 | CSNK1D (0.71) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL3102458 | 0.85 | CSNK1D (0.49) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL3102530 | 0.85 | CSNK1D (0.51) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL3102415 | 0.85 | MAPK14 (0.52) | MAPK14CSNK1DMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217600-B1 | FUNGICIDAL BICYCLIC PYRAZOLES | DU PONT (US) | 2012-12-05 | — | — | EP | claimed |
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | US | claimed |
| EP-2217600-B1 | FUNGICIDAL BICYCLIC PYRAZOLES | DU PONT (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8288375-B2 | Fungicidal bicyclic pyrazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-16 | — | — | US | disclosed |
| EP-2409570-A2 | Fungicidal mixtures based on pyrazolopyridine compounds | BASF SE (DE) | 2012-01-25 | — | — | EP | disclosed |
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | CYP1B1, CBR1, CYP1A1 | MAPK14 3609/4885CSNK1D 1670/4885MAPK13 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.