Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.39 |
| ▸ | PPARA | Q07869 | 17/20 | 0.39 |
| ▸ | PPARG | P37231 | 11/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22091380 | 1.00 | PPARD (0.39) | PPARDPPARAPPARGMMP13MMP14 | |
| SCHEMBL30947259 | 0.92 | PPARD (0.37) | PPARDPPARAPPARG | |
| SCHEMBL22091356 | 0.92 | PPARD (0.37) | PPARDPPARAPPARG | |
| SCHEMBL22091253 | 0.89 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL29981938 | 0.86 | PPARD (0.38) | PPARDPPARAPPARGMMP13MMP14 | |
| SCHEMBL29093193 | 0.86 | PPARD (0.38) | PPARDPPARAPPARGMMP13MMP14 | |
| SCHEMBL29092900 | 0.86 | PPARD (0.38) | PPARDPPARAPPARGMMP13MMP14 | |
| SCHEMBL29092901 | 0.86 | PPARD (0.38) | PPARDPPARAPPARGMMP13MMP14 | |
| SCHEMBL29981915 | 0.86 | PPARD (0.38) | PPARDPPARAPPARGMMP13MMP14 | |
| SCHEMBL22091102 | 0.85 | EGFR (0.39) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894816-A | 3, 3-Difluoroallylamine or salt thereof and pharmaceutical composition comprising the same | 柳韩洋行 | 2024-11-05 | — | — | CN | disclosed |
| CN-113330001-B | 3, 3-Difluoroallylamine or salt thereof and pharmaceutical composition comprising the same | 柳韩洋行 | 2024-07-02 | — | — | CN | disclosed |