Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 5/20 | 0.64 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.64 |
| ▸ | PDE1A | P54750 | 4/20 | 0.64 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.64 |
| ▸ | PDE5A | O76074 | 3/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5061553 | 1.00 | PDE9A (0.64) | PDE9APDE1CPDE1APDE1BPDE5A | |
| Hydrochloric Acid SCHEMBL6864925 | 0.99 | PDE9A (0.63) | PDE9APDE1CPDE1APDE1BPDE5A | |
| SCHEMBL30947390 | 0.90 | PDE9A (0.77) | PDE9APDE1CPDE1APDE1BPDE5A | |
| SCHEMBL5064284 | 0.90 | PDE9A (0.77) | PDE9APDE1CPDE1APDE1BPDE5A | |
| Hydrochloric Acid SCHEMBL6756650 | 0.90 | PDE9A (0.76) | PDE9APDE1CPDE1APDE1BPDE5A | |
| SCHEMBL5065561 | 0.85 | PDE9A (0.53) | PDE9APDE1CPDE1APDE1BPDE5A | |
| SCHEMBL30947399 | 0.85 | PDE9A (0.53) | PDE9APDE1CPDE1APDE1BPDE5A | |
| Hydrochloric Acid SCHEMBL6756750 | 0.84 | PDE9A (0.52) | PDE9APDE1CPDE1APDE1BPDE5A | |
| SCHEMBL5067596 | 0.82 | PDE9A (0.65) | PDE9APDE1CPDE1APDE1BPDE5A | |
| SCHEMBL30947387 | 0.82 | PDE9A (0.65) | PDE9APDE1CPDE1APDE1BPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618980-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | Freedom Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | claimed |
| WO-2024107445-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | FREEDOM BIOSCIENCES, INC. (US) | 2024-05-23 | — | — | WO | claimed |
| EP-4618980-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | Freedom Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107445-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | FREEDOM BIOSCIENCES, INC. (US) | 2024-05-23 | — | — | WO | disclosed |