Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528144 | 1.00 | MAPT (0.43) | MAPTALDH1A1CYP3A4BLMPMP22 | |
| SCHEMBL28528143 | 1.00 | MAPT (0.43) | MAPTALDH1A1CYP3A4BLMPMP22 | |
| SCHEMBL28528146 | 1.00 | MAPT (0.43) | MAPTALDH1A1CYP3A4BLMPMP22 | |
| SCHEMBL28535077 | 0.90 | MAPT (0.44) | MAPTALDH1A1SIRT6SMN1; SMN2RAB9A | |
| SCHEMBL28907758 | 0.90 | MAPT (0.44) | MAPTALDH1A1SIRT6SMN1; SMN2RAB9A | |
| SCHEMBL28535079 | 0.90 | MAPT (0.44) | MAPTALDH1A1SIRT6SMN1; SMN2RAB9A | |
| SCHEMBL28907759 | 0.90 | MAPT (0.44) | MAPTALDH1A1SIRT6SMN1; SMN2RAB9A | |
| SCHEMBL28535078 | 0.90 | MAPT (0.44) | MAPTALDH1A1SIRT6SMN1; SMN2RAB9A | |
| SCHEMBL28533547 | 0.87 | MAPT (0.50) | MAPTALDH1A1SIRT6SMN1; SMN2KMT2A | |
| SCHEMBL28525541 | 0.87 | MAPT (0.50) | MAPTALDH1A1SIRT6SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |